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MilliporeSigma

112194

Sigma-Aldrich

Hexachloro-1,3-butadiene

96%

Sinónimos:

Perchlorobutadiene

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About This Item

Fórmula lineal:
CCl2=CClCCl=CCl2
Número de CAS:
Peso molecular:
260.76
Beilstein/REAXYS Number:
1766570
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

vapor pressure

0.2 mmHg ( 20 °C)

Quality Level

assay

96%

form

liquid

refractive index

n20/D 1.555 (lit.)

bp

210-220 °C (lit.)

mp

−22-−19 °C (lit.)

density

1.665 g/mL at 25 °C (lit.)

functional group

chloro

SMILES string

Cl\C(Cl)=C(Cl)/C(Cl)=C(\Cl)Cl

InChI

1S/C4Cl6/c5-1(3(7)8)2(6)4(9)10

InChI key

RWNKSTSCBHKHTB-UHFFFAOYSA-N

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Application

Hexachloro-1,3-butadiene was used to study the effect of anethol dithiolthione (ADT) on hexachloro-1,3-butadiene (HCBD)-induced nephrotoxicity in rats.

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Los clientes también vieron

L Bouthillier et al.
Toxicology and applied pharmacology, 139(1), 177-185 (1996-07-01)
Administration of anethol dithiolthione (ADT) to rodents can afford protection against some chemically induced toxicities. The aim of the present study was to assess the effects of ADT on hexachloro-1,3-butadiene (HCBD)-induced nephrotoxicity in the rat and to determine the mechanism
Chon-Lin Lee et al.
Chemosphere, 58(11), 1503-1516 (2005-02-08)
Forty sediments were analyzed for chlorobenzenes (CBs) and hexachlorobutadiene (HCBD) to investigate their pollution topography along the Kaohsiung coast, Taiwan. Maximum CB concentrations found, varied from 15.4ng/gdw for 1,2,3-TCB to 56.8ng/gdw for 1,2,4-TCB, while higher HCBD concentrations were detected among
Lachlan H Yee et al.
Biodegradation, 21(6), 947-956 (2010-04-13)
The biodegradation of chlorinated organics in vadose zone soils is challenging owing to the presence of oxygen, which inhibits reductive dehalogenation reactions and consequently the growth of dehalorespiring microbes. In addition, the hydraulic conductivity of vadose zone soils is typically
Trevor Green et al.
Toxicology letters, 138(1-2), 63-73 (2003-02-01)
Hexachloro-1,3-butadiene (HCBD) has been reported to be toxic to the rat kidney in a 2 year study at doses higher than 0.2 mg/kg/day. The toxicity is known to be a consequence of the metabolism of HCBD by glutathione conjugation and
Patrizia Cristofori et al.
Toxicologic pathology, 35(2), 270-275 (2007-03-17)
The correspondence between histopathological findings and segment-specific biomarkers was investigated in rats treated with segment-specific nephrotoxicants. Male Wistar rats were treated with a single injection of K2Cr2O7 (25 mg/kg s.c. in saline), cis-Pt (10 mg/kg i.p. in buffered MSO) or

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