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MilliporeSigma

NCOR2

nuclear receptor corepressor 2

Sinónimos:
CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1
Especie:
ID UniProtKB:
ID del gen:
  • Human(9612) Summary: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
  • Mouse(20602) nuclear receptor co-repressor 2
  • Rat(360801) nuclear receptor co-repressor 2
  • Zebrafish(561503) nuclear receptor co-repressor 2
  • chicken(416815) nuclear receptor corepressor 2
  • cow(538549) nuclear receptor corepressor 2
  • Horse(100059253) nuclear receptor corepressor 2
  • domestic cat(101083973) nuclear receptor corepressor 2
  • dog(486242) nuclear receptor corepressor 2
  • domestic guinea pig(100720194) nuclear receptor corepressor 2
  • naked mole-rat(101702626) nuclear receptor corepressor 2
  • sheep(101121042) nuclear receptor corepressor 2

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-NCOR2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

immunohistochemistry
Anti-SMRTe Antibody, Upstate®, from rabbit,
Reactividad de especies
human
Aplicación
ChIP
immunocytochemistry

western blot
Anti-SMRT Antibody, clone 1SM-1E7, ascites fluid, clone 1SM-1E7, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
ChIPAb+ SMRT - ChIP Validated Antibody and Primer Set, ascites fluid, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
ChIP
electrophoretic mobility shift assay

immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot

Proteins

Referencia del producto
Descripción
Especie
NCOR2/SMRT human, recombinant, expressed in E. coli, ≥60% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human NCOR2,
Especie
human