CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
Sinónimos:
CAMKA
Especie:
Human CAMK2A (815), Mouse Camk2a (12322), Rat Camk2a (25400), Domestic Rabbit CAMK2A (100341507), naked mole-rat Camk2a (101722229), domestic guinea pig Camk2a (100727059), Zebrafish camk2a (550436), chicken CAMK2A (374175), dog CAMK2A (612941), cow CAMK2A (530719) ...Más
ID UniProtKB:
ID del gen:
- Human(815) Summary: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
- Mouse(12322) calcium/calmodulin-dependent protein kinase II alpha
- Rat(25400) calcium/calmodulin-dependent protein kinase II alpha
- Domestic Rabbit(100341507) calcium/calmodulin-dependent protein kinase II alpha
- naked mole-rat(101722229) calcium/calmodulin-dependent protein kinase II alpha
- domestic guinea pig(100727059) calcium/calmodulin-dependent protein kinase II alpha
- Zebrafish(550436) calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
- chicken(374175) calcium/calmodulin-dependent protein kinase II alpha
- dog(612941) calcium/calmodulin-dependent protein kinase II alpha
- cow(530719) calcium/calmodulin-dependent protein kinase II alpha
- Horse(100071654) calcium/calmodulin-dependent protein kinase II alpha
- domestic cat(101084342) calcium/calmodulin-dependent protein kinase II alpha
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Small Molecule - Antagonist
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CaM Kinase II Antibody, α subunit, clone 6G9, clone 6G9, Upstate®, from mouse,
Reactividad de especies
bovine, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-CAMK2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse, clone 6G9, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
mouse, rat
Aplicación
immunofluorescence
western blot
western blot
Monoclonal Anti-CAMK2A antibody produced in mouse, clone 2C4, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anticuerpo anti-fosfo-CaM cinasa II, subunidad α, (Thr286), clon 22B1, clone 22B1, Upstate®, from mouse,
Reactividad de especies
rat
Aplicación
western blot
Small Molecule - Inhibitor
Proteins
Referencia del producto
Descripción
Especie
CAMK2α, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
esiRNA
Small Molecule - Substrate
Referencia del producto
Descripción
Especie
Autocamtide 2-related inhibitory peptide, ≥97% (HPLC), lyophilized powder,
Especie
mouse, rat, human