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Key Documents

1491004

USP

土霉素

United States Pharmacopeia (USP) Reference Standard

同義詞:

土霉素 二水合物

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About This Item

經驗公式(希爾表示法):
C22H24N2O9 · 2H2O
CAS號碼:
分子量::
496.46
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

oxytetracycline

製造商/商標名

USP

應用

pharmaceutical (small molecule)

格式

neat

SMILES 字串

O.[H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C

InChI

1S/C22H24N2O9.H2O/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);1H2/t12-,13-,14+,17+,21-,22+;/m1./s1

InChI 密鑰

IBZHEBHGZFICKS-IFLJXUKPSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Oxytetracycline USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Oxytetracycline Hydrochloride
  • Oxytetracycline Injection
  • Oxytetracycline Tablets
  • Oxytetracycline for Injection
  • Oxytetracycline Hydrochloride Capsules
  • Oxytetracycline Hydrochloride Soluble Powder

生化/生理作用

Antibiotic produced by Streptomyces rimosus.
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Health hazardEnvironment

訊號詞

Warning

危險聲明

危險分類

Aquatic Chronic 2 - Repr. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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存取文件庫

Hrvoje Petković et al.
Microbiology and molecular biology reviews : MMBR, 70(3), 704-728 (2006-09-09)
From a genetic standpoint, Streptomyces rimosus is arguably the best-characterized industrial streptomycete as the producer of oxytetracycline and other tetracycline antibiotics. Although resistance to these antibiotics has reduced their clinical use in recent years, tetracyclines have an increasing role in
Support vector regression for determination of component of compound oxytetracycline powder on near-infrared spectroscopy.
Tingting Zou et al.
Analytical biochemistry, 355(1), 1-7 (2006-05-26)
Extralabel use of oxytetracycline.
T Martin-Jimenez et al.
Journal of the American Veterinary Medical Association, 211(1), 42-44 (1997-07-01)
Lauren B Pickens et al.
The Journal of biological chemistry, 285(36), 27509-27515 (2010-06-05)
Oxytetracycline (OTC) is a broad-spectrum antibiotic that acts by inhibiting protein synthesis in bacteria. It is an important member of the bacterial aromatic polyketide family, which is a structurally diverse class of natural products. OTC is synthesized by a type
Shin-Young Park et al.
Journal of biomedical materials research. Part A, 103(1), 38-47 (2014-03-13)
Peri-implantitis is a chronic inflammatory process with advanced bone loss and impaired healing potential. For peri-implantitis treatment, tissue engineering can be applied to enhance bone regeneration of peri-implant defects. This study aimed to evaluate ex vivo bone morphogenetic protein 2

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