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1445470

USP

Mometasone furoate

United States Pharmacopeia (USP) Reference Standard

同義詞:

(11β,16α)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione

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About This Item

經驗公式（希爾表示法）:
C27H30Cl2O6
CAS號碼:
83919-23-7
分子量：:
521.43
MDL號碼:
MFCD00866003
分類程式碼代碼:
41116107
PubChem物質ID:
329750487
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

mometasone

製造商／商標名

USP

應用

pharmaceutical (small molecule)

形式

neat

SMILES 字串

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c5ccco5)C(=O)CCl

InChI

1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1

InChI 密鑰

WOFMFGQZHJDGCX-ZULDAHANSA-N

基因資訊

human ... NR3C1(2908)

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Mometasone furoate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

生化／生理作用

Mometasone furoate is an anti-inflammatory glucocorticoid.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H360D

危險分類

Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number

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I Haj-Salem et al.
Allergy, 70(2), 212-219 (2014-12-03)
Allergic asthma is characterized by inflammation and airway remodeling. Bronchial epithelium is considered a key player in coordinating airway wall remodeling. In mild asthma, the epithelium is damaged and fails to proliferate and to repair, whereas in severe asthma, the
William E Berger
Expert review of respiratory medicine, 5(6), 739-746 (2011-11-16)
Mometasone furoate and formoterol fumarate dihydrate (MF/F) administered via metered-dose inhaler with a dose counter is a new fixed-dose combination of an inhaled corticosteroid and a long-acting β2-agonist indicated for daily maintenance therapy in patients aged ≥12 years with persistent
Jill P Karpel et al.
Current medical research and opinion, 23(11), 2897-2911 (2007-10-10)
Mometasone furoate (MF), a potent synthetic inhaled corticosteroid (ICS) with a high affinity for the glucocorticoid receptor, is approved for use in the treatment of asthma. Publications reviewed in this article were identified via searches of MEDLINE and EMBASE databases
Kelli Hart et al.
Respirology (Carlton, Vic.), 14(8), 1166-1172 (2009-10-13)
To examine the evidence for the efficacy of once daily dosing of mometasone furoate (MF) and to establish the dose-response relationship for MF in asthma. Meta-analysis of double-blind, randomized controlled clinical trials, identified through a Medline and EMBASE search, comparing
Günther Hochhaus
Clinical therapeutics, 30(1), 1-13 (2008-03-18)
Mometasone furoate nasal spray (MFNS) is recommended as a first-line therapy for allergic rhinitis. The purpose of intranasal administration is to deliver maximally effective therapy to the affected nasal tissues while minimizing systemic exposure. This article reviews the pharmacokinetic and
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