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重要文件

1136002

USP

克林霉素 盐酸盐

United States Pharmacopeia (USP) Reference Standard

同義詞:

Clindamycin hydrochloride monohydrate, (7S)-7-Chloro-7-deoxylincomycin hydrochloride monohydrate

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About This Item

經驗公式(希爾表示法):
C18H33ClN2O5S · HCl · H2O
CAS號碼:
分子量::
479.46
MDL號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

clindamycin

製造商/商標名

USP

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

SMILES 字串

S([C@H]1O[C@@H]([C@@H]([C@@H]([C@H]1O)O)O)[C@H](NC(=O)[C@H]2[N+H](C[C@@H](C2)CCC)C)[C@@H](Cl)C)C.[Cl-].O

InChI

1S/C18H33ClN2O5S.ClH.H2O/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H;1H2/t9-,10+,11-,12+,13-,14+,15+,16+,18+;;/m0../s1

InChI 密鑰

KWMXKEGEOADCEQ-WNNJHRBUSA-N

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一般說明

Clindamycin is a lincosamide antibiotic which is considered as a semisynthetic derivative of lincomycin. It is mainly used as an antimicrobial agent.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Clindamycin hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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D W Scott et al.
The Canadian veterinary journal = La revue veterinaire canadienne, 39(12), 753-756 (1998-12-23)
Clindamycin hydrochloride capsules (11 mg/kg body weight, q24 h) were administered orally to 20 dogs with deep staphylococcal pyoderma. Response to therapy was excellent in 100% of the dogs. Duration of therapy varied from 21 to 91 d, with an
D Gonzalez et al.
Clinical pharmacology and therapeutics, 96(4), 429-437 (2014-06-21)
Clindamycin is commonly prescribed to treat children with skin and skin-structure infections (including those caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA)), yet little is known about its pharmacokinetics (PK) across pediatric age groups. A population PK analysis was performed in
Cutaneous botryomycosis diagnosed long after an arm injury.
Norma Mechow et al.
Journal of the American Academy of Dermatology, 71(4), e155-e156 (2014-09-16)
Katrin Schilcher et al.
The Journal of infectious diseases, 210(3), 473-482 (2014-02-15)
The Gram-positive human pathogen Staphylococcus aureus causes a variety of human diseases such as skin infections, pneumonia, and endocarditis. The micrococcal nuclease Nuc1 is one of the major S. aureus virulence factors and allows the bacterium to avoid neutrophil extracellular
Nicole Berwald et al.
The American journal of emergency medicine, 32(7), 768-771 (2014-05-06)
The benefit of antibiotic prophylaxis for simple hand lacerations (lacerations that do not involve special structures) has not been adequately studied. To assess the feasibility of a randomized controlled trial to determine the role of antibiotic prophylaxis in emergency department

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