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Key Documents

51658-U

Supelco

Ascentis® Express 90Å C8 (2 μm) HPLC Columns

L × I.D. 10 cm × 2.1 mm UHPLC Column

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About This Item

分類程式碼代碼:
41115700
NACRES:
SB.52

product name

Ascentis® Express C8, 2 μm UHPLC Column, 2 μm particle size, L × I.D. 10 cm × 2.1 mm

材料

stainless steel column

品質等級

agency

suitable for USP L7

產品線

Ascentis®

特點

endcapped

製造商/商標名

Ascentis®

包裝

1 ea of

參數

1000 bar max. pressure (14500 psi)
60 °C temp. range

技術

LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

長度 × 內徑

10 cm × 2.1 mm

表面積

120 m2/g

雜質

<5 ppm (metals)

基質

Fused-Core particle platform
superficially porous particle

基質活性組

dimethyloctyl phase

粒徑

2 μm

孔徑

90 Å pore size

pH值

2-9

應用

food and beverages

分離技術

reversed phase

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一般說明

Ascentis® Express 2μm C8 UHPLC columns are based on a 90 Å Fused-Core® particle design. The Fused-Core particle provides a thin porous shell of high-purity silica surrounding a solid silica core. This particle design exhibits very high column efficiency due to the shallow diffusion paths in the 0.4-micron thick porous shell and the small overall particle size of 2-microns. The densely bonded, extensively endcapped dimethyloctyl stationary phase of Ascentis Express 2μm C8 provides a stable, reversed-phase packing that can be used for basic, acidic, or neutral compounds.

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法律資訊

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

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分析證明 (COA)

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Ugandar Reddy Inugala et al.
Journal of chromatographic science, 51(5), 453-459 (2012-10-13)
This paper describes the development of a rapid, novel, stability-indicating gradient reversed-phase high-performance liquid chromatographic method and associated system suitability parameters for the analysis of naproxcinod in the presence of its related substances and degradents using a quality-by-design approach. All
Sreenivasa Rao Chitturi et al.
Journal of pharmaceutical and biomedical analysis, 55(1), 31-47 (2011-02-15)
This paper proposes a simple and selective RP-HPLC method for the determination of process impurities and degradation products (degradants) of atazanavir sulfate (ATV) drug substance. Chromatographic separation was achieved on Ascentis(®) Express C8, (150mm×4.6mm, 2.7μm) column thermostated at 30°C under
Federica Pellati et al.
Journal of pharmaceutical and biomedical analysis, 81-82, 126-132 (2013-05-07)
A closed-vessel microwave-assisted extraction (MAE) technique was optimized for the first time for the extraction of polyphenols from raw propolis. The results obtained by means of response surface experimental design methodology showed that the best global response was reached when
Monika A Olszewska
Journal of separation science, 35(17), 2174-2183 (2012-07-19)
An HPLC method of high resolution has been developed and validated for the simultaneous determination of ten prominent flavonoid aglycones in plant materials using a fused-core C18-silica column (Ascentis® Express, 4.6 mm × 150 mm, 2.7 μm). The separation was
Imran Ali et al.
Biomedical chromatography : BMC, 26(8), 1001-1008 (2012-01-13)
Superficially porous silica particles columns (SPSPCs) are manufactured by different companies. The most common have the brand names Halo, Ascentis Express and Kinetex. These columns provide super fast, sharp peaks and moderate sample loading and back pressure. These are available

文章

When a C18 doesn′t give the desired separation, or your sample contains compounds that are known to be difficult to retain or resolve on a C18, consider changing to an Ascentis® Express C8 column.

When a C18 doesn′t give the desired separation, or your sample contains compounds that are known to be difficult to retain or resolve on a C18, consider changing to an Ascentis® Express C8 column.

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