推薦產品
product name
Discovery® C18 高效液相色谱柱, 5 μm particle size, L × I.D. 25 cm × 4 mm
材料
stainless steel column
agency
suitable for USP L1
產品線
Discovery®
特點
endcapped
製造商／商標名
Discovery®
包裝
1 ea of
標籤範圍
12% Carbon loading
參數
≤70 °C temp. range
400 bar pressure (5801 psi)
技術
HPLC: suitable
LC/MS: suitable
長度 × 內徑
25 cm × 4 mm
表面積
300 m2/g
表面覆盖率
3 μmol/m2
雜質
<10 ppm metals
基質
silica gel, high purity, spherical particle platform
fully porous particle
基質活性組
C18 (octadecyl) phase
粒徑
5 μm
孔徑
180 Å
工作pH值範圍
2-8
應用
food and beverages
分離技術
reversed phase
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一般說明
Discovery® C18 可用于针对 C18 的任何方法。该色谱柱具有对称的峰形、优良的重现性和稳定性等特点，适用于所有常规和高要求的 C18 方法，是此类方法的理想选择。
應用
- Identification, isolation and characterization of dolutegravir forced degradation products and their cytotoxicity potential.: Utilizes the Discovery® C18 HPLC Column to study the stability and degradation of the antiretroviral drug dolutegravir, crucial for ensuring drug safety and efficacy (Saida et al., 2019).
- Rapid, Refined, and Robust Method for Expression, Purification, and Characterization of Recombinant Human Amyloid beta 1-42.: This methodological study leverages the Discovery® C18 HPLC Column for the purification and analysis of amyloid beta peptides, contributing to research on Alzheimer′s disease (Prakash et al., 2019).
- Development and validation of a HPLC electrochemical detection method to measure COMT activity as a tool in drug development.: Showcases the use of the Discovery® C18 HPLC Column in developing a novel analytical method for measuring catechol-O-methyltransferase (COMT) activity, instrumental in the development of psychiatric and neurological medications (Viljoen et al., 2019).
特點和優勢
- 优良的重现性
- 分析酸性和碱性化合物均可获得良好的峰形
- 稳定性好、低流失，适用于 LC-MS 分析
- 能够分离多肽和小分子蛋白质
- 与很多同类 C18 色谱柱相比，疏水性更小，因此分析速度更快
法律資訊
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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相關內容
Discovery C18 and C8 HPLC Columns products offered
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