跳轉至內容
Merck
全部照片(1)

Key Documents

X2628

Sigma-Aldrich

光溜海绵素C

film

同義詞:

XeC

登入查看組織和合約定價


About This Item

線性公式:
C28 H50 N2 O2
CAS號碼:
分子量::
446.71
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

形狀

film

顏色

colorless

溶解度

DMSO: soluble

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@]12CCCCCC[C@@]3([H])CCCN4CC[C@@]([H])(CCCCCC[C@]5([H])CCCN(CC1)[C@@]5([H])O2)O[C@@]34[H]

InChI

1S/C28H50N2O2/c1-3-7-15-25-17-21-30-20-10-14-24(28(30)31-25)12-6-2-4-8-16-26-18-22-29-19-9-13-23(11-5-1)27(29)32-26/h23-28H,1-22H2/t23-,24+,25-,26-,27+,28+/m1/s1

InChI 密鑰

PQYOPBRFUUEHRC-HCKQMYSWSA-N

一般說明

从 Okanowan 海洋海绵中分离得到的大环双-1-氧喹啉脒的合成形式。

生化/生理作用

Xestospongin C 是 IP 3 受体的选择性、可逆性和膜通透性抑制剂。可逆地阻断缓激肽-和氨甲酰胆碱-Ca 2 + 从内质网储存中流出。

特點和優勢

《受体分类和信号转导》手册的 InsP3/Ryanodine 受体页有该化合物的介绍。想要浏览手册的其他页面, 请单击此处

包裝

氮气中包装,密封。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Shaily Malik et al.
Frontiers in molecular neuroscience, 10, 404-404 (2017-12-21)
Human immunodeficiency virus-1 (HIV-1) infection compromises the central nervous system (CNS) in a significant number of infected individuals, resulting in neurological dysfunction that ranges from minor cognitive deficits to frank dementia. While macrophages/microglia are the predominant CNS cells infected by
Hirofumi Morihara et al.
PloS one, 12(12), e0189948-e0189948 (2017-12-22)
Excessive levels of reactive oxygen species (ROS) and impaired Ca2+ homeostasis play central roles in the development of multiple cardiac pathologies, including cell death during ischemia-reperfusion (I/R) injury. In several organs, treatment with 2-aminoethoxydiphenyl borate (2-APB) was shown to have
Martin Prince Alphonse et al.
Journal of immunology (Baltimore, Md. : 1950), 197(9), 3481-3489 (2016-10-04)
Kawasaki disease (KD) is a multisystem vasculitis that predominantly targets the coronary arteries in children. Phenotypic similarities between KD and recurrent fever syndromes point to the potential role of inflammasome activation in KD. Mutations in NLRP3 are associated with recurrent
D B van Rossum et al.
The Journal of biological chemistry, 275(37), 28562-28568 (2000-07-06)
The mechanism for coupling between Ca(2+) stores and store-operated channels (SOCs) is an important but unresolved question. SOC-mediated Ca(2+) entry is complex and may reflect more than one type of channel and coupling mechanism. To assess such possible divergence the
Wenbin Zhong et al.
Nature communications, 7, 12702-12702 (2016-09-02)
Metabolic pathways are reprogrammed in cancer to support cell survival. Here, we report that T-cell acute lymphoblastic leukemia (T-ALL) cells are characterized by increased oxidative phosphorylation and robust ATP production. We demonstrate that ORP4L is expressed in T-ALL but not

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務