跳轉至內容
Merck
全部照片(3)

重要文件

C1530

Sigma-Aldrich

Cyclopiazonic acid

from Penicillium cyclopium, ≥98% (HPLC), powder, sarcoplasmic reticulum Ca²⁺-pump inhibitor

同義詞:

CPA

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C20H20N2O3
CAS號碼:
分子量::
336.38
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.77

產品名稱

环盐酸吗甲吡嗪酸 来源于圆弧青霉菌, ≥98% (HPLC), powder

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

white to off-white

溶解度

DMSO: soluble
chloroform: soluble

儲存溫度

−20°C

SMILES 字串

CN1C(=O)C(=C(\C)O)\C(=O)C2C(Cc3cccc4[nH]cc2c34)C1(C)C

InChI

1S/C20H22N2O3/c1-10(23)15-18(24)17-12-9-21-14-7-5-6-11(16(12)14)8-13(17)20(2,3)22(4)19(15)25/h5-7,9,13,17,21,23H,8H2,1-4H3/b15-10-

InChI 密鑰

WJCPGKDPOYBOOJ-GDNBJRDFSA-N

一般說明

圆弧偶氮酸(CPA)是由多种 曲霉 青霉菌 种合成的tetramic酸。

應用

圆弧青霉菌来源圆弧偶氮酸用于:
  • 作为标准品,用于薄层色谱法(TLC)检测和定量黄曲霉毒素
  • 作为培养基成分,用于不含Ca2+的DMEM(含10%胎牛血清(FBS))
  • 作为肌质网/内质网Ca2+ -ATP酶的可逆抑制剂,检测腔内钙在内质网(ER)-至-高尔基体转运过程中的作用
  • 作为内质网Ca2+-ATP酶的阻滞剂,处理神经元;研究内质网(ER)在Ca2+诱导的Ca2+ 释放(CICR)抑制 SERCA 过程中,对释放和维持Ca2+ 的影响

生化/生理作用

抑制肌质网 Ca 2 + -泵。

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 2 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Plant and fungal toxins as contaminants of feed and meat
Improving the Safety of Fresh Meat, 77-101 (2005)
N Demaurex et al.
The Journal of biological chemistry, 267(4), 2318-2324 (1992-02-05)
The filling state of intracellular Ca2+ stores has been proposed to regulate Ca2+ influx across the plasma membrane in a variety of tissues. To test this hypothesis, we have used three structurally unrelated inhibitors of the Ca(2+)-ATPase of intracellular Ca2+
Toxigenic Aspergillus flavus and other fungi of public health concern in food and organic matter in southwest Nigeria
Fapohunda SO, et al.
Mycology, 3, 210-219 (2012)
Ca2+-Induced Ca2+ Release in Aplysia Bag Cell Neurons Requires Interaction Between Mitochondrial and Endoplasmic Reticulum Stores
Geiger JE, et al.
Journal of Neurophysiology (2008)
Sakiko Ujita et al.
Cerebral cortex (New York, N.Y. : 1991), 27(2), 1602-1614 (2016-01-24)
Astrocytes in various brain regions exhibit spontaneous intracellular calcium elevations both in vitro and in vivo; however, neither the temporal pattern underlying this activity nor its function has been fully evaluated. Here, we utilized a long-term optical imaging technique to

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務