推薦產品
生物源
plant (Withania somnifera)
品質等級
化驗
≥95% (HPLC)
形狀
powder
mp
252-253 °C
官能基
epoxy
ketone
運輸包裝
ambient
儲存溫度
2-8°C
SMILES 字串
C[C@H]([C@H]1CC(C)=C(CO)C(=O)O1)[C@H]2CC[C@H]3[C@@H]4C[C@H]5O[C@]56[C@@H](O)C=CC(=O)[C@]6(C)[C@H]4CC[C@]23C
InChI
1S/C28H38O6/c1-14-11-21(33-25(32)17(14)13-29)15(2)18-5-6-19-16-12-24-28(34-24)23(31)8-7-22(30)27(28,4)20(16)9-10-26(18,19)3/h7-8,15-16,18-21,23-24,29,31H,5-6,9-13H2,1-4H3/t15-,16-,18+,19-,20-,21+,23-,24+,26+,27-,28+/m0/s1
InChI 密鑰
DBRXOUCRJQVYJQ-CKNDUULBSA-N
應用
用醉茄素 A 处理 HEK293 细胞，研究其对囊性纤维化炎症的影响。
生化／生理作用
对肿瘤细胞具有细胞毒性的甾体内酯。保护作用归因于抗脂质过氧化、抗氧化和解毒功能。
醉茄素 A 是从植物中分离得到的甾体内酯 。具有强大的抗炎属性，可抑制 NF-κ 的活化B 信号通路。醉茄素 A 的抗肿瘤活性是由于它能够通过结合膜联蛋白 II 和破坏 F 肌动蛋白交联来改变细胞骨架结构。醉茄素 A 通过与波形蛋白和肌动蛋白结合抑制血管生成。
準備報告
醉茄素 A 在 1 mg/mL 甲醇中生成澄清、无色溶液。
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
438.8 °F
閃點（°C）
226 °C
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條款
Separation of Withanoside IV; Withanoside V; Withaferin A; 12-Deoxywithastramonolide; Withanolide A; Withanolide B
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