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產品名稱
VEGF165, recombinant, expressed in HEK 293 cells, suitable for cell culture
生物源
human
品質等級
重組細胞
expressed in HEK 293 cells
描述
Vascular Endothelial Growth Factor 165 human
化驗
≥95% (SDS-PAGE)
形狀
lyophilized powder
效力
<10 ng/mL ED50
品質
endotoxin tested
分子量
dimer 42 kDa (glycosylated)
包裝
pkg of 10 μg
pkg of 50 μg
技術
cell culture | mammalian: suitable
雜質
<0.075 EU/μg
顏色
white
溶解度
water: soluble
UniProt登錄號
儲存溫度
−20°C
基因資訊
human ... VEGFA(7422)
一般說明
VEGF165 is expressed in human HEK 293 cells as a glycosylated homodimer with an apparent molecular mass of 45 kDa. Production in human HEK 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
生化／生理作用
VEGF165 belongs to the PDGF/VEGF growth factor family characterized by the presence of eight conserved cysteine residues and a cystine knot structure. VEGF is secreted by the majority of tumor cells and initiates angiogenesis by activating endothelial cells of existing blood vessels and promoting their migration.
VEGF has also been implicated in correlation with poor prognosis in breast cancer.
In addition, VEGF is released in rheumatoid arthritis in response to TNF-α, increasing endothelial permeability and stimulating angiogenesis (formation of capillaries).
VEGF has also been implicated in correlation with poor prognosis in breast cancer.
In addition, VEGF is released in rheumatoid arthritis in response to TNF-α, increasing endothelial permeability and stimulating angiogenesis (formation of capillaries).
分析報告
The specific activity was determined by the dose-dependent stimulation of the proliferation of HUVEC cells (human umbilical vein endothelial cells).
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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