推薦產品
生物源
human
品質等級
重組細胞
expressed in E. coli (N-terminal histidine tagged)
化驗
≥95% (GE)
形狀
lyophilized powder
分子量
10.7 kDa
技術
ligand binding assay: suitable
溶解度
Tris-HCl, pH 7.5: 1.0—1.10 mg/mL, clear to slightly hazy, colorless
適合性
suitable for molecular biology
儲存溫度
−20°C
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一般說明
泛素是球形蛋白，由 76 个氨基酸组成，表面具有赖氨酸残基。分子量为 8565 Da。
Research Area: CANCER
Ubiquitin is a highly conserved protein composed of 76 amino acids, and it is expressed universally in all eukaryotes, ranging from yeast to humans.
Ubiquitin is a highly conserved protein composed of 76 amino acids, and it is expressed universally in all eukaryotes, ranging from yeast to humans.
應用
人泛素可作为研究水稻 E3-Ubiquitin 连接酶的分离、鉴定及 OsHOS1 基因在冷应激反应调控中的作用的供试化合物。
泛素（人）可用于：
- 作为底物，用于 体外 泛素化测定
- 作为底物，用于ADP-核糖基化和泛素化测定
- 向新鲜血液补充 64 ng内源性泛素，用于实验分组，研究其对癌症预后的临床潜在影响
生化／生理作用
泛素对真核细胞发挥正常功能起关键作用。参与免疫系统发育和免疫系统功能正常运行。此外，此免疫亲和蛋白还参与调节免疫稳态。泛素肽片段（U50-59）能够阻断细胞免疫和体液免疫。
泛素是存在于真核生物组织中的一种小分子调节蛋白。外源性泛素可以刺激许多细胞系凋亡。人乳头状瘤病毒-16 的 E7 蛋白通过泛素-蛋白酶体途径刺激视网膜母细胞瘤蛋白降解。
Ubiquitin-mediated proteolysis plays an important role in several basic cellular processes including regulation of cell cycle and division, differentiation and development, modulation of cell-surface receptors, the secretory pathway (protein transport), morphogenesis of neuronal networks, transcriptional regulation and signal transduction, transcriptional silencing, DNA repair, long-term memory, and circadian rhythms.
準備報告
泛素人可溶于 0.02 MTris-HCl，浓度为 1.00-1.10 mg/mL，得到澄清至略微浑浊的无色溶液。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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