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Merck
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重要文件

T7313

Sigma-Aldrich

1-[2-(Trifluoromethyl)phenyl]imidazole

同義詞:

TRIM

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About This Item

經驗公式(希爾表示法):
C10H7F3N2
CAS號碼:
分子量::
212.17
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77

生物源

synthetic (organic)

品質等級

化驗

≥98% (GC)

形狀

solid

溶解度

DMSO: soluble 30 mg/mL

儲存溫度

2-8°C

SMILES 字串

FC(F)(F)c1ccccc1-n2ccnc2

InChI

1S/C10H7F3N2/c11-10(12,13)8-3-1-2-4-9(8)15-6-5-14-7-15/h1-7H

InChI 密鑰

WZBWBNCQUTXYEL-UHFFFAOYSA-N

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生化/生理作用

Potent nitric oxide synthase inhibitor. Because of the putative involvement of nitric oxide in depression and stress syndromes, TRIM was studied for its antidepressant effects, and found to reduce manifestations of stress in an animal model as well as fluoxetine.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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Yves Basset et al.
Ecology and evolution, 7(23), 9991-10004 (2017-12-15)
We have little knowledge of the response of invertebrate assemblages to climate change in tropical ecosystems, and few studies have compiled long-term data on invertebrates from tropical rainforests. We provide an updated list of the 72 species of Saturniidae moths
Juan Traba et al.
Scientific reports, 9(1), 9473-9473 (2019-07-03)
Farmland bird populations have strongly declined across Europe over the last decades due to agriculture intensification, despite successive reforms of EU's Common Agricultural Policy (CAP). In parallel, CAP has led to a reduction of fallow land, a critical habitat for
Yong Lin et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(5), 6023-6034 (2019-02-12)
Hepatitis B virus (HBV) replication and envelopment is dependent on cellular autophagy. Previously, we have provided evidence for the extensive lysosomal degradation of HBV virions and the hepatitis B surface antigen (HBsAg), which is likely controlled by autophagosome-lysosome fusion. Synaptosomal-associated
Amélie Wallenhammar et al.
PloS one, 12(7), e0181551-e0181551 (2017-07-29)
Tripartite motif-containing (TRIM) proteins are defined by the sequential arrangement of RING, B-box and coiled-coil domains (RBCC), where the B-box domain is a unique feature of the TRIM protein family. TRIM21 is an E3 ubiquitin-protein ligase implicated in innate immune
Jose A Adams et al.
Resuscitation, 74(3), 516-525 (2007-05-01)
Nitric oxide (NO) is a critical regulator of vascular tone, and signal transduction. NO is produced via three unique synthases (NOS); endothelial (eNOS), and neuronal (nNOS) are both constitutively expressed and inducible (iNOS) produced primarily after stimulation. NO has been

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