T7189

Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

• MDL號碼: MFCD02689206
• 分類程式碼代碼: 51111800
• NACRES: NA.32

屬性

• 生物源: human
• 品質等級: 200
• 重組細胞: expressed in NSO cells
• 化驗: >95% (SDS-PAGE)
• 形狀: lyophilized powder
• 效力: 0.004-0.016 mg per mL ED₅₀
• 分子量: 52.6 kDa
• 包裝: pkg of 50 μg
• 儲存條件: avoid repeated freeze/thaw cycles
• 技術: cell culture | mammalian: suitable
• 雜質: endotoxin, tested
• UniProt登錄號: P20333
• 儲存溫度: −20°C
• 基因資訊: human ... TNFRSF1B(7133)

描述

應用

Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human can be used as a test compound for analyzing the interaction between tumor necrosis factor (TNF) and its two soluble receptors by using surface plasmon resonance (SPR) technique.

生化／生理作用

Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human belongs to TNF family of receptors and mediates the metabolic effects of TNF-α. Tumor Necrosis Factor Soluble Receptor II blocks the TNF-α-induced apoptosis and hence regulates the TNF-α function. It also has a pivotal role in neutralizing the biological activities of both TNF-α and TNF-β.

外觀

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline

分析報告

The biological activity is measured by its ability to neutralize the TNF-α mediated cytotoxicity in mouse L-929 cells in the presence of the metabolic inhibitor actinomycin D.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable