T3439

Tumor Necrosis Factor Soluble Receptor I (TNF sRI)/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

• MDL號碼: MFCD02689207
• 分類程式碼代碼: 51111800
• NACRES: NA.32

屬性

• 生物源: human
• 品質等級: 100
• 重組細胞: expressed in NSO cells
• 化驗: >95% (SDS-PAGE)
• 形狀: lyophilized powder
• 效力: 0.4-1 ng/mL ED₅₀
• 分子量: 48 kDa
• 包裝: pkg of 50 μg
• 儲存條件: avoid repeated freeze/thaw cycles
• 技術: cell culture | mammalian: suitable
• 雜質: endotoxin, tested
• UniProt登錄號: P20333
• 儲存溫度: −20°C
• 基因資訊: human ... TNFRSF1B(7133)

描述

應用

Tumor Necrosis Factor Soluble Receptor I (TNF sRI)/Fc Chimera human may be used to study signaling of apoptosis and NF-κB activation.

生化／生理作用

Tumor Necrosis Factor Soluble Receptor I (TNF sRI)/Fc Chimera human belongs to TNF family of receptors and has a pivotal role in neutralizing the biological activities of both TNF-α and TNF-β. Soluble tumor necrosis factor receptor along with intrathecal interleukin-1 receptor antagonist shows an anti-allodynic action in rat L5 spinal nerve transection model of neuropathic pain.

外觀

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 2.5 mg bovine serum albumin.

分析報告

The biological activity is measured by its ability to neutralize apoptosis of mouse L-929 cells treated with 0.25 ng/ml recombinant human TNF-α.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable