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About This Item
經驗公式（希爾表示法）:
C14H18N4O3 · C3H6O3
CAS號碼:
分子量：:
380.40
EC號碼:
MDL號碼:
分類程式碼代碼:
51285203
PubChem物質ID:
NACRES:
NA.85
推薦產品
品質等級
化驗
≥98%
形狀
powder
儲存條件
(Keep container tightly closed in a dry and well-ventilated place.)
顏色
white
溶解度
H2O: soluble 20 mg/mL
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
作用方式
DNA synthesis | interferes
enzyme | inhibits
儲存溫度
2-8°C
SMILES 字串
CC(O)C(O)=O.COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
InChI
1S/C14H18N4O3.C3H6O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-2(4)3(5)6/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2,4H,1H3,(H,5,6)
InChI 密鑰
IIZVTUWSIKTFKO-UHFFFAOYSA-N
一般說明
化学结构：嘧啶
應用
甲氧苄啶是最主要的抗细菌剂。 它有二氢叶酸还原酶抑制活性和原核酶选择性。 它在临床上被用来治疗尿道感染、轻度急性前列腺炎、复发性膀胱炎、怀孕期间无症状菌尿和呼吸道感染。 乳酸甲氧苄啶用作选择剂。
生化／生理作用
甲氧苄啶和磺胺甲恶唑结合，通过阻碍核苷酸合成，干扰细菌细胞叶酸细胞代谢。 甲氧苄啶和原核生物特异性二氢叶酸还原酶（DHFR）结合，抑制二氢叶酸（DHF）和四氢叶酸（THF）还原。THF是胸腺嘧啶合成途径基本前体，干扰该途径，抑制细菌DNA合成。
其他說明
保存于密闭容器内，置于干燥通风处。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral - Repr. 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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