SRP8030

Fn14 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

• 同義詞: CD266, E1A-associated protein p300, FGF-inducible 14, Tumor necrosis factor receptor superfamily member 12A
• 分類程式碼代碼: 51111800
• NACRES: NA.32

屬性

• 生物源: human
• 重組細胞: expressed in HEK 293 cells
• 化驗: >95% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: ~35 kDa by SDS-PAGE
• 包裝: pkg of 50 μg
• 儲存條件: avoid repeated freeze/thaw cycles
• 雜質: <0.1 EU/μg endotoxin, tested
• 顏色: white
• UniProt登錄號: Q9NP84
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... TNFRSF12A(51330)

描述

一般說明

TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK-Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke.

外觀

Lyophilized from PBS.

重構

Reconstitute with 50 μL deionized water.

其他說明

The extracellular region of human FN14 (aa 28-75) is fused at the C-terminus to the Fc portion of human IgG1.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable