SRP3284

人 GASP-1

recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)

• 同義詞: GDF-associated serum protein-1
• 分類程式碼代碼: 12352200
• NACRES: NA.32

屬性

• 生物源: human
• 重組細胞: expressed in CHO cells
• 化驗: ≥95% (HPLC); ≥95% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: 55.0-66.0 kDa
• 包裝: pkg of 25 μg
• 濃度: 0.0025-0.0040 μg/mL
• 雜質: <0.1 EU/μg endotoxin, tested
• 顏色: white to off-white
• UniProt登錄號: Q8TEU8
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... WFIKKN2(124857)

描述

一般說明

Growth and differentiation factor-associated serum protein-1 (GASP-1) is expressed primarily in the ovary, testis, and brain. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain. Recombinant human GASP-1 is a 542 amino acid protein that migrates at an apparent molecular weight of approximately 55-66kDa by SDS-PAGE analysis under non-reducing conditions.

生化／生理作用

Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-β binding protein that contains multiple protease inhibitor structural domains. It can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin-A.

外觀

Lyophilized from 10 mM Sodium Phosphate, pH 7.8.

重構

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable