生物源
human
重組細胞
expressed in baculovirus infected Sf9 cells
化驗
≥20% (SDS-PAGE)
形狀
aqueous solution
分子量
90.5 kDa
包裝
pkg of 50 μg
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... TNFAIP3(7128)
一般說明
人A20，也称为肿瘤坏死因子α诱导蛋白3（TNFAIP3）或含有OTU结构域的蛋白7C（OTUD7C），（GenBank登录号NM_006290）氨基酸2-791（末端），带有N-末端标记标签，MW=90.5 kDa，通过杆状病毒表达系统在Sf9昆虫细胞中表达。
應用
可用于研究酶动力学、抑制剂筛选和选择性分析。
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Jing Liu et al.
Journal of biomedical science, 20, 74-74 (2013-10-09)
Intestinal polyps may further develop into colon cancer; the pathogenesis is not clear. The p53 gene is an important anti-cancer gene in the body, which is suppressed in cancer. The ubiquitin E3 ligase A20 (A20) plays a role in regulating
Chong-Shan Shi et al.
Autophagy, 6(7), 986-987 (2010-08-28)
Toll-like receptor 4 (TLR4) signaling triggers autophagy, which has been linked to both adaptive and innate immunity. Engagement of TLR4 recruits to the receptor complex Beclin 1, a key component of a class III phosphatidylinositol 3-kinase complex (PI3KC3) that initiates
Sarah G Hymowitz et al.
Nature reviews. Cancer, 10(5), 332-341 (2010-04-13)
Clinicians have suspected for hundreds of years that chronic activation of the immune system contributes to the development of cancer. However, the molecular mechanisms that mediate this precarious interplay are only now being elucidated. Recent reports have identified A20 as
Rita M Tavares et al.
Immunity, 33(2), 181-191 (2010-08-14)
A20 is a ubiquitin modifying enzyme that restricts NF-kappaB signals and protects cells against tumor necrosis factor (TNF)-induced programmed cell death. Given recent data linking A20 (TNFAIP3) with human B cell lymphomas and systemic lupus erythematosus (SLE), we have generated
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