SML3823

KCI807

≥98% (HPLC)

• 同義詞: 5,3’-Dihydroxyflavone, 5-Hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-one
• 經驗公式（希爾表示法）: C₁₅H₁₀O₄
• CAS號碼: 6665-68-5
• 分子量：: 254.24
• MDL號碼: MFCD00143394
• 分類程式碼代碼: 51111800
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: 0.2 mg/mL (DMSO:EtOH (2:1),clear, warmed, clear colorless solution)
• 儲存溫度: room temp
• SMILES 字串: [o]1c2c([c](cc1c3cc(ccc3)O)=O)c(ccc2)O
• InChI 密鑰: SZMQXDYEGKRZDG-UHFFFAOYSA-N

描述

生化／生理作用

Cell penetrant, selective and potent inhibitor of the androgen receptor (AR)-ELK1 interaction

KCI807 is a cell penetrant, selective and potent inhibitor of the androgen receptor (AR)-ELK1 interaction. KCI807 interrupts association of the androgen receptor (AR) with transcription activator ELK1 (ETS family transcription factor ELK1). It potently suppresses growth of enzalutamide-resistant prostate cancer tumor xenografts in rodents.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable