SML3808

Firategrast

≥98% (HPLC)

• 同義詞: SB 683699, T 0047, T-0047, (αS)-α-[(2,6-Difluorobenzoyl)amino]-4′-(ethoxymethyl)-2′,6′-dimethoxy[1,1′-biphenyl]-4-propanoic acid, (S)-2-(2,6-Difluorobenzamido)-3-(4′-(ethoxymethyl)-2′,6′-dimethoxy-[1,1′-biphenyl]-4-yl)propanoic acid, SB-683699
• 經驗公式（希爾表示法）: C₂₇H₂₇F₂NO₆
• CAS號碼: 402567-16-2
• 分子量：: 499.50
• 分類程式碼代碼: 51111800
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C

描述

生化／生理作用

Firategrast is an orally available, potent and selective antagonist of α4β1/α4β7 integrins. Firategrast inhibits α4β1/α4β7 integrin-mediated transferring of lymphocytes into the central nervous system (CNS). In phase II trial it demonstrated a reduction of new contrast enhancing MRI lesions in patients with relapsing remitting MS.

Orally available, potent and selective antagonist of α4β1/α4β7 integrins

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable