SML3696

DHMEQ

≥98% (HPLC)

• 同義詞: 2-Hydroxy-N-[2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]benzamide, DHM2EQ, Dehydroxymethylepoxyquinomicin, rel-2-Hydroxy-N-[(1R,2R,6R)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]benzamide
• 經驗公式（希爾表示法）: C₁₃H₁₁NO₅
• CAS號碼: 287194-38-1
• 分子量：: 261.23
• MDL號碼: MFCD23135615
• 分類程式碼代碼: 12352200

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: O[C@@H]1[C@@]2([H])[C@](C(C=C1NC(C3=C(C=CC=C3)O)=O)=O)([H])O2

描述

生化／生理作用

Potent, selective, and irreversible inhibitor of NF-κB that covalently binds to a cysteine residue.



DHMEQ is a potent, selective, and irreversible inhibitor of NF-κB that covalently binds to a cysteine residue. It inhibits inflammatory cytokine expression in mice models. DHMEQ is a potent and non/low toxic in vivo anti-inflammatory agent effective in number of animal models.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302,H315,H317,H319,H335
• 防範說明: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable