SML3571

GS-621763

≥98% (HPLC)

• 同義詞: (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2-cyano-5-((isobutyryloxy)methyl)tetrahydrofuran-3,4-diyl bis(2-methylpropanoate)
• 經驗公式（希爾表示法）: C₂₄H₃₁N₅O₇
• CAS號碼: 2647442-13-3
• 分子量：: 501.53
• 分類程式碼代碼: 51111800
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: N#C[C@@]1(C2=CC=C3C(N)=NC=NN32)O[C@@H]([C@H]([C@H]1OC(C(C)C)=O)OC(C(C)C)=O)COC(C(C)C)=O

描述

生化／生理作用

GS-621763 is an orally bioavailable analog of remdesivir, which is efficiently converted in plasma to active metabolite GS-441524, or in lungs to the bioactive triphosphate GS-443902. GS-621763 effectively reduces SARS-CoV-2 burden to near-undetectable levels in ferrets.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable