SML3478

PNU-159682

≥95% (HPLC)

• 同義詞: (8S,10S)-7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4′,3′:4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-5,12-naphthacenedione, PNU 159682
• 經驗公式（希爾表示法）: C₃₂H₃₅NO₁₃
• CAS號碼: 202350-68-3
• 分子量：: 641.62
• MDL號碼: MFCD12756329
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: powder
• 儲存條件: under inert gas
• 顏色: , Faint red to very dark red
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: -10 to -25°C

描述

生化／生理作用

Highly potent anthracycline toxin

PNU-159682, an active nemorubicin metabolite, is a highly potent anthracycline toxin that retains antitumor activity in vivo. Similarly to other anthracyclines PNU-159682 intercalates between the CG base pairs of DNA, but the stability of the complexes is much higher.

安全資訊

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H301,H341,H351,H360FD
• 防範說明: P202 - P264 - P270 - P280 - P301 + P310 - P405
• 危險分類: Acute Tox. 3 Oral - Carc. 2 - Muta. 2 - Repr. 1B
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable