SML2906

ERGi-USU

≥98% (HPLC)

• 同義詞: 1-[2-(2-Thiazolyl)diazenyl]-2-naphthalenol, 1-[2-Thiazolylazo]-2-naphthol, NSC139021, TAN
• 經驗公式（希爾表示法）: C₁₃H₉N₃OS
• CAS號碼: 1147-56-4
• 分子量：: 255.30
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: faint brown to dark red
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: −20°C
• InChI: 1S/C13H9N3OS/c17-11-6-5-9-3-1-2-4-10(9)12(11)15-16-13-14-7-8-18-13/h1-8,17H
• InChI 密鑰: IOMXCGDXEUDZAK-UHFFFAOYSA-N

描述

生化／生理作用

ERGi-USU is a selective and potent inhibitor of growth of ERG positive cancer cell lines, while spearing normal prostate or endothelial cells. It potently inhibits growth of ERG positive VCaP xenografts in mice. ERGi-USU is a potent and selective ligand of the ribosomal atypical kinase RIOK2 (right open reading frame (RIO) kinase 2) that induces ribosomal stress.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3