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390062

Sigma-Aldrich

噻唑橙

Dye content ~90 %

同義詞:

1-甲基-4-[(3-甲基-2(3H)-苯并噻唑基)甲基]喹啉 对甲苯磺酸

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About This Item

經驗公式（希爾表示法）:
C26H24N2O3S2
CAS號碼:
107091-89-4
分子量：:
476.61
MDL號碼:
MFCD00192499
分類程式碼代碼:
12171500
PubChem物質ID:
24864313
NACRES:
NA.47

形狀

powder

品質等級

200

成份

Dye content, ~90%

技術

titration: suitable

mp

270 °C (dec.) (lit.)

λmax

512 nm

應用

diagnostic assay manufacturing
hematology
histology

儲存溫度

room temp

SMILES 字串

Cc1ccc(cc1)S([O-])(=O)=O.CN2C(\Sc3ccccc23)=C\c4cc[n+](C)c5ccccc45

InChI

1S/C19H17N2S.C7H8O3S/c1-20-12-11-14(15-7-3-4-8-16(15)20)13-19-21(2)17-9-5-6-10-18(17)22-19;1-6-2-4-7(5-3-6)11(8,9)10/h3-13H,1-2H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1

InChI 密鑰

ACOJCCLIDPZYJC-UHFFFAOYSA-M

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相關類別

一般說明

噻唑橙可与肽核酸连接，用于检测均质溶液中的目标核酸。它是一种染料并且具有良好网织红细胞染料的预测物理特性和生物染色特征，因此，它被作为一种用于网织红细胞分析的染料。它在与核酸结合后，特别是RNA，产生大幅的荧光增强和高量子产率。它不会发生沉淀，并且可以透过活细胞膜。

應用

噻唑橙已可用于染色并定量网织红细胞。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H319,H335

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
SHBN3550
MKCK2354
MKCJ3723
MKCH5294
MKCD3904

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Phong Lan Thao Tran et al.
Biochimie, 93(8), 1288-1296 (2011-06-07)
The potential formation of G-quadruplexes in many regions of the genome makes them an attractive target for drug design. A large number of small molecules synthesized in recent years display an ability to selectively target and stabilize G-quadruplexes. To screen for
Adam D Cawte et al.
Nature communications, 11(1), 1283-1283 (2020-03-11)
RNA molecules play vital roles in many cellular processes. Visualising their dynamics in live cells at single-molecule resolution is essential to elucidate their role in RNA metabolism. RNA aptamers, such as Spinach and Mango, have recently emerged as a powerful
Danitza Nébor et al.
Scientific reports, 8(1), 12793-12793 (2018-08-26)
Anemic Nan mice carry a mutation (E339D) in the second zinc finger of erythroid transcription factor KLF1. Nan-KLF1 fails to bind a subset of normal KLF1 targets and ectopically binds a large set of genes not normally engaged by KLF1
Eeman Khorramian et al.
Shock (Augusta, Ga.), 48(4), 490-497 (2017-04-30)
Intensive care unit (ICU) anemia is an extreme version of anemia of inflammation that occurs commonly in critically ill patients and is associated with increased morbidity and mortality. Currently available therapies for ICU anemia have shown inconsistent efficacies in clinical
Costimulation blockade, busulfan, and bone marrow promote titratable macrochimerism, induce transplantation tolerance, and correct genetic hemoglobinopathies with minimal myelosuppression.
Adams AB
Journal of Immunology, 167(2), 1103-1111 (2001)
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