SML2834

SGC-CAMKK2-1

≥98% (HPLC)

• 同義詞: 2-Cyclopentyl-4-(5-(m-tolyl)furo[2,3-b]pyridin-3-yl)benzoic acid, YL-36
• 經驗公式（希爾表示法）: C₂₆H₂₃NO₃
• CAS號碼: 2561494-76-4
• 分子量：: 397.47
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: CC1=CC(C2=CN=C(OC=C3C4=CC(C5CCCC5)=C(C(O)=O)C=C4)C3=C2)=CC=C1

描述

生化／生理作用

SGC-CAMKK2-1 (YL-36) is a potent and selective CaM kinase kinase (CaMKK) inhibitor (CAMKK2 IC₅₀ = 30 nM) that inhibits C4-2 cellular AMPK phosphorylation (IC₅₀ = 1.6 μM) with selective affinity toward CAMKK1/2 over other kinases (404-kinase panel kinome-wide Discoverx screen).

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable