SML2557

Aminopyridine 2

≥98% (HPLC)

• 同義詞: 1-((6-Aminopyridin-3-yl)methyl)-3-(4-bromophenyl)urea
• 經驗公式（希爾表示法）: C₁₃H₁₃BrN₄O
• CAS號碼: 2411643-58-6
• 分子量：: 321.17
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: NC1=CC=C(CNC(NC2=CC=C(Br)C=C2)=O)C=N1
• InChI: 1S/C13H13BrN4O/c14-10-2-4-11(5-3-10)18-13(19)17-8-9-1-6-12(15)16-7-9/h1-7H,8H2,(H2,15,16)(H2,17,18,19)
• InChI 密鑰: NNDXEGUWCFIHTD-UHFFFAOYSA-N

描述

生化／生理作用

Aminopyridine 2 (1-((6-aminopyridin-3-yl)methyl)-3-(4-bromophenyl)urea) is an orally available, potent and selective irreversible inhibitor of myeloperoxidase (MPO) that blocks vasomotor dysfunction in rat aortic rings. Aminopyridine 2 inhibits myeloperoxidase in a mouse model of peritonitis.

orally available, potent and selective irreversible inhibitor of myeloperoxidase (MPO)

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable