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Key Documents

SML2308

Sigma-Aldrich

硫酸阿扎那韦 硫酸酯

≥95% (HPLC)

同義詞:

(3S,8S,9S,12S)-1,14-Dimethyl-3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-pentaazatetradecanedioate sulfate

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About This Item

經驗公式(希爾表示法):
C38H52N6O7 · H2SO4
CAS號碼:
分子量::
802.93
分類程式碼代碼:
12352200
NACRES:
NA.77

化驗

≥95% (HPLC)

形狀

powder

光學活性

[α]/D -40 to -50°, c = 1 in methanol: water (1:1)

儲存條件

desiccated

顏色

white to beige

溶解度

H2O: 2 mg/mL, clear

運輸包裝

wet ice

儲存溫度

2-8°C

SMILES 字串

O[C@@H](CN(CC1=CC=C(C2=CC=CC=N2)C=C1)NC([C@@H](NC(OC)=O)C(C)(C)C)=O)[C@@H](NC([C@@H](NC(OC)=O)C(C)(C)C)=O)CC3=CC=CC=C3.O=S(O)OO

InChI

1S/C38H52N6O7.H2O4S/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28;1-5(2,3)4/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47);(H2,1,2,3,4)/t29-,30-,31+,32+;/m0./s1

InChI 密鑰

DQSGVVGOPRWTKI-QVFAWCHISA-N

尋找類似的產品? 前往 產品比較指南

生化/生理作用

Atazanavir sulfate is the prodrug of Atazanavir, an antiviral HIV protease inhibitor.

象形圖

Health hazardCorrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - STOT RE 1

標靶器官

Heart,Liver

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Jose R Castillo-Mancilla et al.
The Journal of antimicrobial chemotherapy, 71(6), 1609-1618 (2016-02-20)
The multinational PEARLS (ACTG A5175) study, conducted mainly in resource-limited settings, identified an increased treatment failure rate among HIV-infected individuals randomized to once-daily unboosted atazanavir, didanosine-EC, and emtricitabine compared with efavirenz-based regimens. We evaluated associations between selected human genetic polymorphisms
Vincent Calvez et al.
The Journal of antimicrobial chemotherapy, 72(1), 19-28 (2016-09-23)
For many patients living with HIV-1, the efficacy of combined ART (cART) has made the infection turn to a chronic disease. Because cART is associated with a risk of long-term toxicity, switching patients with virological success to another therapy remains
Lisa Rosenblatt et al.
BMC infectious diseases, 16, 492-492 (2016-09-20)
A previous cohort study indicated that atazanavir (ATV), a protease inhibitor used for HIV treatment, is not associated with an increased risk of cardiovascular (CV) events. The objective of this study was to compare the risk of CV events among

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