SML2087

SJ000291942

≥98% (HPLC)

• 同義詞: 2-(4-Ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)-acetamide
• 經驗公式（希爾表示法）: C₁₆H₁₅FN₂O₄
• CAS號碼: 425613-09-8
• 分子量：: 318.30
• MDL號碼: MFCD02219567
• 分類程式碼代碼: 12352202
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: CCC1=CC=C(OCC(NC2=CC([N+]([O-])=O)=C(F)C=C2)=O)C=C1
• InChI: 1S/C16H15FN2O4/c1-2-11-3-6-13(7-4-11)23-10-16(20)18-12-5-8-14(17)15(9-12)19(21)22/h3-9H,2,10H2,1H3,(H,18,20)
• InChI 密鑰: YSZJLXPXVFGTNK-UHFFFAOYSA-N

描述

生化／生理作用

Activator of Bone Morphogenetic Protein (BMP) signaling

SJ000291942 is an activator of Bone Morphogenetic Protein (BMP) signaling with an EC50 value < 1 μM. Bone Morphogenetic Proteins (BMPs) are a group of growth factors and cytokines were originally discovered by their ability to induce the formation of bone and cartilage, but are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. SJ000291942 was shown to ventralize zebrafish embryos, activate SMAD1/5/8 phosphorylation, and induce the differentiation of C2C12 myoblasts to osteoblasts in manner consistent with BMP4 activation.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3