SML1626

TFCA

≥98% (HPLC)

• 同義詞: 3-(3,4-Dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]-2-propenamide, N-(4-Trifluoromethylphenyl) 3,4-dimethoxycinnamamide
• 經驗公式（希爾表示法）: C₁₈H₁₆F₃NO₃
• CAS號碼: 895700-18-2
• 分子量：: 351.32
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825510
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 25 mg/mL, clear
• 儲存溫度: room temp
• SMILES 字串: O=C(NC1=CC=C(C(F)(F)F)C=C1)/C=C/C2=CC=C(OC)C(OC)=C2
• InChI: 1S/C18H16F3NO3/c1-24-15-9-3-12(11-16(15)25-2)4-10-17(23)22-14-7-5-13(6-8-14)18(19,20)21/h3-11H,1-2H3,(H,22,23)/b10-4+
• InChI 密鑰: KFWWXJZNIMFFRO-ONNFQVAWSA-N

描述

生化／生理作用

TFCA is a Liver X receptor α (LXRα) antagonist that reduces lipid accumulation and fatty liver in mice. Apparently TFCA binds to the LXR? ligand binding domain and induces interaction with NCoR corepressor.

TFCA is a Liver X receptor α (LXRα) antagonist.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable