SML1616

ICA-069673

≥98% (HPLC)

• 同義詞: ICA 069673, N-(2-Chloro-5-pyrimidinyl)-3,4-difluoro-benzamide
• 經驗公式（希爾表示法）: C₁₁H₆ClF₂N₃O
• CAS號碼: 582323-16-8
• 分子量：: 269.63
• MDL號碼: MFCD20926351
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825502
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: room temp
• SMILES 字串: O=C(C1=CC=C(F)C(F)=C1)NC2=CN=C(Cl)N=C2
• InChI: 1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)
• InChI 密鑰: IIBSHMFXVWTQSJ-UHFFFAOYSA-N

描述

生化／生理作用

ICA-069673 has higher selectivity towards KV7.2/KV7.3 heterodimeric channels than KV7.3/KV7.5 channels. ICA-069673 is considered as a part of gating modifiers.

ICA-069673 is an orally active, potent and selective KV7.2/KV7.3 (KCNQ2/Q3) channel opener that is active in rodent epilepsy models.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3