SML1145

ML303

≥98% (HPLC)

• 同義詞: 2-Methoxy-4-(3-methyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenol
• 經驗公式（希爾表示法）: C₂₁H₁₆F₃N₃O₂
• CAS號碼: 1638211-04-7
• 分子量：: 399.37
• 分類程式碼代碼: 12352202
• PubChem物質ID: 329825679
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: CC1=NN(C2=CC=C(C(F)(F)F)C=C2)C3=NC=CC(C4=CC=C(O)C(OC)=C4)=C31
• InChI: 1S/C21H16F3N3O2/c1-12-19-16(13-3-8-17(28)18(11-13)29-2)9-10-25-20(19)27(26-12)15-6-4-14(5-7-15)21(22,23)24/h3-11,28H,1-2H3
• InChI 密鑰: YBRHGNCGFMRGSV-UHFFFAOYSA-N

描述

生化／生理作用

It belongs to the pyrazolopyridine family.

ML303 is a potent inhibitor (IC₅₀ = 155 nM) of the influenza viral protien NS1. NS1 enhances virulence by inhibiting host cell immune responses, including the expression of IFN-b, and regulating synthesis, splicing and translation of viral RNA.

ML303 is a potent inhibitor of the influenza viral protien NS1.

安全資訊

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P264 - P270 - P301 + P310 - P405 - P501
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable