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Key Documents

SML1002

Sigma-Aldrich

青藤碱 盐酸盐

≥98% (HPLC)

同義詞:

(9a,13a,14a)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-morphinan-6-one hydrochloride, Cucoline hydrochloride, Kukolin hydrochloride

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About This Item

經驗公式(希爾表示法):
C19H23NO4 · HCl
CAS號碼:
分子量::
365.85
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

生物源

plant (Sinomenium acutum)

化驗

≥98% (HPLC)

形狀

powder

光學活性

[α]/D -70 to -90°, c = 1 in H2O

藥物控制

regulated under CDSA - not available from Sigma-Aldrich Canada

顏色

white to beige

溶解度

H2O: 20 mg/mL, clear

儲存溫度

2-8°C

SMILES 字串

OC1=C(OC)C=CC(C2)=C1[C@]3(CC(C(OC)=C4)=O)[C@@]4([H])[C@H]2N(C)CC3.Cl

InChI

1S/C19H23NO4.ClH/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19;/h4-5,9,12-13,22H,6-8,10H2,1-3H3;1H/t12-,13+,19-;/m1./s1

InChI 密鑰

YMEVIMJAUHZFMW-VUIDNZEBSA-N

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生化/生理作用

Sinomenine is a herbal medicine used to treat inflammatory diseases like rheumatoid arthritis. Sinomenine had anti-inflammatory effects in several animal models of inflammation, and inhibits mast cell degranulation and histamine release. Additionally, Sinomenine potentiates renewal of human embryonic stem cells.

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Yuting Xu et al.
Artificial cells, nanomedicine, and biotechnology, 47(1), 4131-4138 (2019-11-09)
Background: Accumulating evidence displays that sinomenine hydrochloride (SH) are utilised to treat a variety of cancers. Nevertheless, the influences of SH on ovarian cancer stay blurry. We endeavoured to uncover the antitumor effects of SH on ovarian cancer and underlying

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