SML0876

Filastatin

≥98% (HPLC)

• 同義詞: (3-Chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone
• 經驗公式（希爾表示法）: C₁₈H₁₈ClN₃O₃
• CAS號碼: 431996-53-1
• 分子量：: 359.81
• 分類程式碼代碼: 51111800
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 15 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: Clc1c(ccc(c1)C(=O)N2CCN(CC2)c3ccc(cc3)[N+](=O)[O-])C
• InChI: 1S/C18H18ClN3O3/c1-13-2-3-14(12-17(13)19)18(23)21-10-8-20(9-11-21)15-4-6-16(7-5-15)22(24)25/h2-7,12H,8-11H2,1H3
• InChI 密鑰: PNECWWUOUHGWQG-UHFFFAOYSA-N

描述

生化／生理作用

Filastatin blocks the ability of Candida albicans, and other Candida sp. to bind to polystyrene, and human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal morphologic transition through inhibition of the hyphal-specific promoter HWP1.

Filastatin is an inhibitor of Candida albicans surface binding, morphology transition and biofilm formation.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable