SML0803

VUF10661

≥98% (HPLC)

• 同義詞: (3S)-N-[(1S)-5-Amino-1-[[(2,2-diphenylethyl)amino]carbonyl]pentyl]-2-(1,4-dioxo-4-phenylbutyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
• 經驗公式（希爾表示法）: C₄₀H₄₄N₄O₄
• CAS號碼: 914291-63-7
• 分子量：: 644.80
• 分類程式碼代碼: 51111800
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 10 mg/mL, clear
• 儲存溫度: −20°C

描述

生化／生理作用

VUF10661 is a potent agonist of the chemokine receptor CXCR3. VUF10661 induces receptor internalization, recruitment of ?-arrestins and activates Gi proteins with similar potency to endogenous CXCL ligands.

特點和優勢

This compound is featured on the Chemokine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301,H315,H319,H335,H413
• 防範說明: P273 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 3 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable