SML0507

NPC26

≥98% (HPLC)

• 同義詞: 4,5,6,7-Tetrahydro-5,5,7,7-tetramethyl-2-[[(5-nitro-2-thienyl)carbonyl]amino]-thieno[2,3-c]pyridine-3-carboxylic acid ethyl ester, NPC-26
• 經驗公式（希爾表示法）: C₁₉H₂₃N₃O₅S₂
• CAS號碼: 864860-32-2
• 分子量：: 437.53
• MDL號碼: MFCD04428321
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825516
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: light orange to dark orange
• 溶解度: DMSO: 2 mg/mL, clear (warmed)
• 儲存溫度: 2-8°C
• SMILES 字串: CCOC(=O)c1c2CC(C)(C)NC(C)(C)c2sc1NC(=O)c3ccc(s3)[N+]([O-])=O
• InChI: 1S/C19H23N3O5S2/c1-6-27-17(24)13-10-9-18(2,3)21-19(4,5)14(10)29-16(13)20-15(23)11-7-8-12(28-11)22(25)26/h7-8,21H,6,9H2,1-5H3,(H,20,23)
• InChI 密鑰: DWGSXNATVAGHKZ-UHFFFAOYSA-N

描述

生化／生理作用

NPC26 induces mitochondrial fragmentation and cell death in RAS expressing cells, similar to erastin. The effects of NPC26 are independent of ROS scavengers, which can block cell death induced by erastin.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable