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About This Item
經驗公式（希爾表示法）:
C10H7IN2
CAS號碼:
分子量：:
282.08
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推薦產品
化驗
≥97% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 10 mg/mL (clear solution, warmed)
儲存溫度
−20°C
SMILES 字串
Ic1cc(ncn1)-c2ccccc2
InChI
1S/C10H7IN2/c11-10-6-9(12-7-13-10)8-4-2-1-3-5-8/h1-7H
InChI 密鑰
ZTCJXHNJVLUUMR-UHFFFAOYSA-N
應用
在 体外 迁移测定中，4-IPP 已被用作条件培养基 (CM) 中的巨噬细胞的迁移抑制因子 (MIF)。
生化／生理作用
4- IPP是细胞渗透、有效的巨噬细胞迁移抑制因子（MIF）拮抗剂，共价修饰MIF的N末端脯氨酸。
4-碘代-6-苯基嘧啶 (4-IPP) 有可能成为一种新的抗多倍体治疗剂，可在甲状腺癌患者中用于靶向多倍体肿瘤细胞。它可通过阻断IMF-κB途径抑制破骨细胞的生成。4-IPP 可作为巨噬细胞迁移抑制因子 (MIF) 的治疗靶点，用于治疗病理性溶骨性骨病和绝经后骨质流失。它可以阻止肺腺癌细胞的发育和运动，并可以刺激甲状腺癌的细胞凋亡和有丝分裂死亡。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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