SML0461

PH-002

≥98% (HPLC)

• 同義詞: 4-[[4-[[2-(3,4-Dihydro-3-methyl-4-oxo-1-phthalazinyl)acetyl]amino]phenyl]methyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester, PH 002, PH002
• 經驗公式（希爾表示法）: C₂₇H₃₃N₅O₄
• CAS號碼: 1311174-68-1
• 分子量：: 491.58
• MDL號碼: MFCD22666400
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329824739
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 10 mg/mL (clear solution)
• 儲存溫度: 2-8°C
• SMILES 字串: O=C(N1CCN(CC2=CC=C(NC(CC3=NN(C)C(C4=C3C=CC=C4)=O)=O)C=C2)CC1)OC(C)(C)C
• InChI: 1S/C27H33N5O4/c1-27(2,3)36-26(35)32-15-13-31(14-16-32)18-19-9-11-20(12-10-19)28-24(33)17-23-21-7-5-6-8-22(21)25(34)30(4)29-23/h5-12H,13-18H2,1-4H3,(H,28,33)
• InChI 密鑰: GSXXTLWPQMHHDJ-UHFFFAOYSA-N

描述

生化／生理作用

PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells that restores mitochondrial cytochrome c oxidase subunit 1 levels, rescues impairments of mitochondrial motility and neurite outgrowth. PH-002 is an apoE4 structure corrector that reverses the apoE4 detrimental effects.

PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction; apoE4 structure corrector.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable