SML0397

DR2313

≥98% (HPLC)

• 同義詞: 3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one
• 經驗公式（希爾表示法）: C₈H₁₀N₂OS
• CAS號碼: 284028-90-6
• 分子量：: 182.24
• MDL號碼: MFCD08703132
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825393
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: H₂O: >2 mg/mL (warmed)
• 儲存溫度: 2-8°C
• SMILES 字串: CC1=NC(=O)C2=C(CCSC2)N1
• InChI: 1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11)
• InChI 密鑰: HRYKZAKEAVZGJD-UHFFFAOYSA-N

描述

生化／生理作用

DR2313 is a PARP inhibitor.

DR2313 is a PARP-1; PARP-2 inhibitor (Ki = 0.23 mM). DR2313 has neuroprotective effects in both in vivo and in vitro ischemic models, and reduces cortical infarct volume in focal ischemia in rats.

特點和優勢

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable