品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
faintly yellow to dark yellow
溶解度
DMSO: >5 mg/mL (warmed)
儲存溫度
−20°C
SMILES 字串
CN1C(C(=O)Nc2ccccn2)=C(O)c3sc(Cl)cc3S1(=O)=O
InChI
1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)
InChI 密鑰
WLHQHAUOOXYABV-UHFFFAOYSA-N
一般說明
Lornoxicam belongs to the oxicam class. It has anti-inflammatory and antipyretic properties. Lornoxicam prevents the synthesis of prostaglandin (PG) by inhibiting cyclo-oxygenase. It is used to relieve various types of symptoms associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute sciatica and low back pain.
應用
Lornoxicam has been used as a drug in melanin binding study with cassette dosing and rapid equilibrium dialysis inserts.
生化/生理作用
Lornoxicam is an oxicam-class NSAID with strong analgesic properties.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 2 Oral
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Drug delivery, 19(5), 255-263 (2012-07-11)
The aim of this study was to investigate the joint tissue distribution and pharmacodynamics of Lornoxicam (Lnxc) following intra-articular injection of either Lnxc suspensions or sustained release Lnxc-loaded PLGA microspheres (Lnxc-MS), as well as the biocompatibility of PLGA microspheres with
European journal of oral implantology, 5(2), 165-173 (2012-08-07)
To assess the efficacy of quick-release lornoxicam (LNX) on patient-reported acute pain after dental implant surgery. The study included subjects in good general health, aged 18 to 65 and scheduled to receive a maximum of three implants in the same
World journal of surgery, 36(9), 2039-2044 (2012-05-16)
The aim of this prospective, randomized, double-blind study was to determine the more effective supplemental analgesic, paracetamol or lornoxicam, for postoperative pain relief after lower abdominal surgery. Sixty patients scheduled for lower abdominal surgery under general anesthesia were randomly allocated
Bratislavske lekarske listy, 113(4), 211-213 (2012-04-17)
Lornoxicam and iv paracetamol are commonly preferred to be used for postoperative analgesia. Although Aspirin is a well known non-steroid anti-inflammatory drug that decreases the erythrocyte deformability, there is no study comparing lornoxicam and iv paracetamol regarding their effects on
Pakistan journal of pharmaceutical sciences, 25(2), 371-375 (2012-03-31)
A rapid, isocratic stability indicating high performance liquid chromatographic method was developed and validated for the estimation of lornoxicam in its powder for injection. The analysis was performed on a Shimadzu VP-ODS (4. 6 mm x 15 cm, 5 µm)
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