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Merck
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SML0255

Sigma-Aldrich

4-DAMP

≥98% (HPLC)

同義詞:

1,1-二甲基-4-二苯基乙酰氧基哌啶碘化物, 4-[(二苯基乙酰基)氧基] -1,1-二甲基碘化哌啶, 4-二苯乙酰氧基-N-甲基-哌啶甲碘化物, 4-二苯基乙酰氧基-N-甲基哌啶甲硫醇

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About This Item

經驗公式（希爾表示法）:
C21H26INO2
CAS號碼:
1952-15-4
分子量：:
451.34
MDL號碼:
MFCD00078564
分類程式碼代碼:
12352200
PubChem物質ID:
329825263
NACRES:
NA.77

品質等級

100

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: ≥15 mg/mL

儲存溫度

room temp

SMILES 字串

[I-].C[N+]1(C)CCC(CC1)OC(=O)C(c2ccccc2)c3ccccc3

InChI

1S/C21H26NO2.HI/c1-22(2)15-13-19(14-16-22)24-21(23)20(17-9-5-3-6-10-17)18-11-7-4-8-12-18;/h3-12,19-20H,13-16H2,1-2H3;1H/q+1;/p-1

InChI 密鑰

WWJHRSCUAQPFQO-UHFFFAOYSA-M

生化／生理作用

4-DAMP 是 M3 型选择性胆碱能受体拮抗剂。

特點和優勢

该化合物在受体分类和信号转导手册的 乙酰胆碱受体（毒蕈碱） 页面上有详细描述。想要浏览手册的其他页面， 请单击此处。
这种化合物是神经科学研究的特色产品。点击此处发现更多特色神经科学产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
075M4727V
114M4722V
062M4721V
022M4719V

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Qiang Liu et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 44(3), 907-919 (2017-11-28)
Overactive bladder associated with bladder outlet obstruction (BOO) is a highly prevalent condition, which is usually treated with antimuscarinics. However, the potential effects of antimuscarinics on the structure and function of bladder have not been investigated thus far. Sprague-Dawley(R) rats
Mohammad Zarei et al.
The International journal of neuroscience, 129(12), 1203-1212 (2019-08-09)
Purpose of the study: Kaempferol (KM) is a flavonoid found in plant-derived foods and medicinal plants. Recently, it is well established that KM plays a protective role to develop Alzheimer's disease. The current study aimed at evaluating the effect of
Shohei Yamaguchi et al.
Food chemistry, 276, 376-382 (2018-11-10)
Our previous results (Nakamura et al., 2013, 2016) indicated that acetylcholine (ACh) in orally administered foods exerts antihypertensive effects. Eggplants (Solanum melongena) contain abundant ACh (Horiuchi et al., 2003), and their food functionality was discovered, using spontaneously hypertensive rats, by
A Koarai et al.
The European respiratory journal, 39(3), 698-704 (2011-09-03)
Macrophages increase in number and are highly activated in chronic obstructive pulmonary disease (COPD). Muscarinic receptor antagonists inhibit acetylcholine-stimulated release of neutrophilic chemoattractants, suggesting that acetylcholine may regulate macrophage responses. Therefore, expression and function of components of the non-neuronal cholinergic
Mojtaba Mohseni et al.
Veterinary research forum : an international quarterly journal, 8(2), 115-120 (2017-08-09)
Displacement of the abomasum is a common disease of the gastrointestinal tract in dairy cattle. Abomasal displacement has been associated with abomasal hypomotility. Therefore, it is necessary to identify effective therapeutic agents that stimulate abomasal motility in cattle. Yarrow (
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