SML0007

Cevimeline hydrochloride hemihydrate

≥95% (HPLC, NMR)

• 同義詞: AF-102B, SNI-2011
• 經驗公式（希爾表示法）: C₁₀H₁₇NOS · xHCl · yH₂O
• CAS號碼: 153504-70-2
• 分子量：: 199.31 (anhydrous free base basis)
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825084
• NACRES: NA.77

屬性

• 化驗: ≥95% (HPLC, NMR)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to tan
• 溶解度: H₂O: ≥25 mg/mL
• 起源: Daiichi-Sankyo
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• SMILES 字串: O.Cl.Cl.C[C@@H]1O[C@@]2(CS1)CN3CC[C@H]2CC3.C[C@@H]4O[C@@]5(CS4)CN6CC[C@H]5CC6
• InChI: 1S/2C10H17NOS.2ClH.H2O/c2*1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11;;;/h2*8-9H,2-7H2,1H3;2*1H;1H2/t2*8-,10-;;;/m11.../s1
• InChI 密鑰: ZSTLCHCDLIUXJE-GMLJRNIPSA-N

描述

應用

Cevimeline hydrochloride hemihydrate may be used in cell signaling studies.

生化／生理作用

Cevimeline is a muscarinic M1 and M3 receptor agonist. Cevimeline stimulates secretion by the salivary glands and is used to treat the symptoms of dry mouth.

Cevimeline stimulates the peripheral muscarinic acetylcholine receptors of salivary glands and increases the concentration of Ca⁺² in parotic acini and duct cells of rats. It thus acts as therapeutic agent for xerostomia.

特點和優勢

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Daiichi-Sankyo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全資訊

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P264 - P270 - P301 + P310 - P405 - P501
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable