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Key Documents

SMB01042

Sigma-Aldrich

Allocryptopin

≥90% (LC/MS-ELSD)

同義詞:

β-Allocryptopine, γ-Homochelidonine, Fagarine I

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About This Item

經驗公式(希爾表示法):
C21H23NO5
CAS號碼:
分子量::
369.41
MDL號碼:
分類程式碼代碼:
12352205
NACRES:
NA.25

生物源

plant

化驗

≥90% (LC/MS-ELSD)

形狀

solid

分子量

369.41

溶解度

water: slightly soluble

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

−20°C

InChI

1S/C21H23NO5/c1-22-7-6-14-9-19-20(27-12-26-19)10-15(14)17(23)8-13-4-5-18(24-2)21(25-3)16(13)11-22/h4-5,9-10H,6-8,11-12H2,1-3H3

InChI 密鑰

HYBRYAPKQCZIAE-UHFFFAOYSA-N

一般說明

Allocryptopin, an isoquinoline alkaliod, is a natural product commonly available from Allocryptopinus japonicus, Glaucium arabicum, Zanthoxylum beecheyanum, Berberis integerrima, and Macleaya cordata. This secondary metabolite derived from plant sources exhibits various biological activities such as anti-inflammatory, antiviral, and antitumor properties.

應用

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

生化/生理作用

Allocryptopine has been reported to possess strong antibacterial, anti-inflammatoty, antiparasitic, antineoplastic and anti-addictive activities. Allocryptopine inhibits human acetylcholinesterase and butyrylcholinesterase. It blocks hERG current in HEK293 cells. Allocryptopine strongly enhanced the I(peak) of the T353I channel by enhancing the plasma membrane (PM) expression of Nav1.5 and rescued defective trafficking after co-incubation with HEK293 cells that carry mutation channel 24 h.

特點和優勢

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

其他說明

For additional information on our range of Biochemicals, please complete this form.

儲存類別代碼

11 - Combustible Solids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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