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重要文件

SCP0147

FR-1, cyclic

Name: FR-1, cyclic
Brand: SIGMA

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About This Item

經驗公式（希爾表示法）:

C₃₅H₅₇N₁₃O₁₆S₂

分子量：:

980.03

分類程式碼代碼:

12352202

NACRES:

NA.32

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Sigma-Aldrich

P4274

Poly(Lys, Tyr) hydrobromide

化驗

≥95% (HPLC)

形狀

lyophilized

成份

Peptide Content, ≥78%

儲存條件

protect from light

儲存溫度

−20°C

Amino Acid Sequence

Cys-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Cys

應用

FR-1 is a cyclic RGDS peptide that acts via binding to FR-1 receptor, a 57 kDa Arg-Gly-Asp-Ser (RGDS)-binding protein involved in early embryogenesis.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Histological distribution of FR-1, a cyclic RGDS-peptide, binding sites during early embryogenesis, and isolation and initial characterization of FR-1 receptor in the sand dollar embryo.

H Katow et al.

Development, growth & differentiation, 39(2), 207-219 (1997-04-01)

A fibronectin-related synthetic cyclic H-Cys-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Cys-OH (RGDSPASS) peptide (FR-1) binding site in the embryo of the sand dollar Clypeaster japonicus was specified using dansyl-labeled FR-1 (Dns-FR-1) and horseradish peroxidase-labeled FR-1, and an FR-1 receptor was isolated using FR-1-affinity column chromatography. The

An RGDS peptide-binding receptor, FR-1R, localizes to the basal side of the ectoderm and to primary mesenchyme cells in sand dollar embryos.

H Katow et al.

Development, growth & differentiation, 43(5), 601-610 (2001-09-29)

Immunoblotting using polyclonal antibodies (pAb) raised against an FR-1 receptor (FR-1R), a 57 kDa Arg-Gly-Asp-Ser (RGDS)-binding protein, of the sand dollar Clypeaster japonicus showed that the pAb monospecifically bound to the protein. FR-1R was present in purified plasma membrane, suggesting

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