推薦產品
化驗
≥95% (HPLC)
形狀
lyophilized
成份
Peptide Content, ≥75%
儲存條件
protect from light
儲存溫度
−20°C
Amino Acid Sequence
Ac-Bhg-Leu-Asp-Ile-Ile-Trp
應用
PD-145065 is used as an endothelin-A/endothelin-B (ETA/ETB) receptor antagonist.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Paulo Castro-Chaves et al.
European journal of pharmacology, 544(1-3), 91-96 (2006-07-18)
We analyzed the influence of endothelin-1 and endocardial endothelium on the myocardial effects of angiotensin-II. Angiotensin-II (10(-9)-10(-5) M) was tested in rabbit right papillary muscles in absence (Protocol-A) or presence of PD-145065 (10(-7) M; Protocol-B), BQ-123 (10(-7) M; Protocol-C) or
Comparison of 2 endothelin-receptor antagonists on in vitro responses of equine palmar digital arterial and venous rings to endothelin-1.
Stokes AM, Venugopal CS, Hosgood G, et al.
Canadian Journal of Veterinary Research = Revue Canadienne De Recherche Veterinaire, 7-, 197-205 (2006)
K E Todd et al.
Surgery, 122(2), 443-449 (1997-08-01)
Endothelin peptides are polykines with strong vasoconstrictor properties. We have previously shown that endothelin antagonism (PD145065) reduces the local severity of acute pancreatitis. We now investigated the effect of endothelin antagonism on systemic inflammation in a model of acute hemorrhagic
Francesca Ceccarelli et al.
Biochemical pharmacology, 65(5), 783-793 (2003-03-12)
Expression and pharmacological properties of endothelin receptors (ETRs) were investigated in H9c2 cardiomyoblasts. The mechanism of receptor-mediated modulation of intracellular Ca(2+) concentration ([Ca(2+)](i)) was examined by measuring fluorescence increase of Fluo-3-loaded cells with flow cytometry. Binding assays showed that [125I]endothelin-1
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