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Merck
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重要文件

SCP0091

Sigma-Aldrich

Caspase 9 Substrate, chromogenic

≥95% (HPLC), lyophilized

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About This Item

經驗公式(希爾表示法):
C29H38N8O11
分子量::
674.66
分類程式碼代碼:
12352202
NACRES:
NA.32

產品名稱

Caspase 9 Substrate, chromogenic, ≥95% (HPLC)

化驗

≥95% (HPLC)

形狀

lyophilized

成份

Peptide Content, ≥75%

儲存條件

protect from light

儲存溫度

−20°C

Amino Acid Sequence

Ac-Leu-Glu-His-Asp-pNA

應用

Caspase 9 is an initiator caspase that cleaves procaspase 3 and procaspase 7 to propagate the apoptotic cascade. Caspase 9 may be detected using a variety of chromogenic and fluorogenic peptide substrates built around the LEHD peptide core such as the chromogenic substrate Ac-LEHD-pNa (Ac-Leu-Glu-His-Asp-p-nitroanalide).

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Yinyuan Wu et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 27(5), 539-546 (2011-06-22)
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Psoriasis is a chronic inflammatory skin disease affecting 1-3% of the world's population. Traditional Chinese medicines have been extensively used for treating psoriasis with promising clinical results. Celastrol, a triterpenoid isolated from a Chinese herb Celastrus orbiculatus caulis, has been
Juan Liu et al.
Molecular cancer, 10, 95-95 (2011-08-02)
Caspase-8 is a key upstream mediator in death receptor-mediated apoptosis and also participates in mitochondria-mediated apoptosis via cleavage of proapoptotic Bid. However, the role of caspase-8 in p53- and p73-dependent apoptosis induced by genotoxic drugs remains unclear. We recently reported
Aza-derivatives of resveratrol are potent macrophage migration inhibitory factor inhibitors.
Fujita, Y., et al.
Investigational New Drugs (2011)

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