SBR00057

Retapamulin

≥98% (HPLC)

• 經驗公式（希爾表示法）: C₃₀H₄₇NO₄S
• CAS號碼: 224452-66-8
• 分子量：: 517.76
• MDL號碼: MFCD11045316
• 分類程式碼代碼: 51284706
• NACRES: NA.76

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 抗生素活性譜: Gram-positive bacteria
• 作用方式: protein synthesis | interferes
• 儲存溫度: −20°C
• InChI: 1S/C30H47NO4S/c1-7-28(4)16-24(35-25(33)17-36-22-14-20-8-9-21(15-22)31(20)6)29(5)18(2)10-12-30(19(3)27(28)34)13-11-23(32)26(29)30/h7,18-22,24,26-27,34H,1,8-17H2,2-6H3/t18-,19+,20-,21+,22?,24-,26+,27+,28-,29+,30+/m1/s1
• InChI 密鑰: STZYTFJPGGDRJD-FJJJPKKESA-N

描述

一般說明

Retapamulin (RET) is a semi-synthetic antibiotic ointment, and pleuromutilin derivative compound. The primary structural difference between pleuromutilin and retapamulin is in the C-14 side chain.

生化／生理作用

Retapamulin is a potent antibacterial agent against Gram-positive bacteria, especially against Staphylococcus aureus and S. pyogenes. It displays synergistic effects against Enterococcus faecalis in combination with streptogramin (MLS). RET initiates ribosomal arrests at the start codon and enables genes to use alternative translational sites in E. coli.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable