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Key Documents

SAB5702978

Sigma-Aldrich

Anti-FMRP Antibody, clone 4Y8I5, Rabbit Monoclonal

同義詞:

FMRP, FRAXA, POF, POF1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

材料

colorless

無性繁殖

4Y8I5, monoclonal

形狀

liquid

分子量

70-80 kDa

物種活性

human, rat, rat

濃度

0.5 mg/mL

技術

immunohistochemistry: 1:50 - 1:200
immunoprecipitation (IP): 1:50 - 1:200
western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACD

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... FMR1(2332)

一般說明

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FMRP (Q06787).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IHC, IP

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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